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Propargyl-Gly(m-PEG4)-Val-Ala-PAB(m-PEG8)-Exatecan val such as amino acids

SKU: 49267606232

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Description

such as amino acids

Product Name HaXS8 Synonyms CAS Number Related CAS Molecular Formula C35H43ClF4N6O8 Molecular Weight 787

89 SMILES ClCCOCCOCCOCC(=O)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

SB-715992 CAS Number 336113-53-2 Related CAS Molecular Formula C30H33ClN4O2 Molecular Weight 517

Propargyl-Gly(m-PEG4)-Val-Ala-PAB(m-PEG8)-Exatecan val such as amino acidsSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The

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